What is classified as a multifeed anticoagulant?

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Bromadiolone is classified as a multifeed anticoagulant because it requires multiple feedings to achieve its lethal effects on rodent populations. This type of anticoagulant works by interfering with the blood's ability to clot, leading to internal bleeding and eventual death in rodents. The mechanism involves inhibiting vitamin K epoxide reductase, which is essential for the synthesis of certain clotting factors.

Multifeed anticoagulants are designed to be consumed over several days, which allows for the rodent to take multiple doses without immediate detection by non-target species. This contrasts with some acute rodenticides, which typically require just one feeding to be effective but can pose a higher risk to non-target animals and human health due to rapid lethality.

While Warfarin is also an anticoagulant, it is considered a first-generation anticoagulant, similar to Bromadiolone, which is a second-generation product, providing enhanced potency and efficacy. The mention of an acute rodenticide relates to a class that operates differently, requiring only one feeding, and IGRs (Insect Growth Regulators) are not rodenticides at all, as they target insect development rather than blood coagulation.

Overall, Bromadiolone's classification

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